Regis students come from a wide range of socio-economic backgrounds - over 40% are the sons of immigrants. All students commute to Regis; the average trip between home and school is one hour (each way). In 2021-22 students came from:
| Bronx | 37 | Staten Island | 12 | |||
| Brooklyn | 37 | Westchester/Upstate/CT | 84 | |||
| Manhattan | 133 | Long Island | 73 | |||
| Queens | 69 | New Jersey | 92 | |||
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