Regis students come from a wide range of socioeconomic backgrounds; over 40 percent are the sons of immigrants. All students commute to Regis; the average trip between home and school is one hour (each way). In 2023–24, students came from:
| Bronx | 43 | Staten Island | 16 | |||
| Brooklyn | 38 | Westchester/Upstate/Connecticut | 80 | |||
| Manhattan | 141 | Long Island | 66 | |||
| Queens | 69 | New Jersey | 79 | |||
|
||||||
